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FRAMEWORK
Before applying RIGOROUS, identify your research task
RIGOROUS begins by asking what kind of question your study is trying to answer. EHR studies may appear similar on the surface, but different research tasks require different estimands, assumptions, analyses, validity checks, and language.
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Description
Estimate the occurrence or distribution of a health state, event, exposure, or practice in a defined population.
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Signal Discovery
Scan many exposures, features, drugs, variants, or outcomes to identify candidate signals for further study.
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Factual Prediction
Predict current or future outcomes under observed or expected care conditions.
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Counterfactual Prediction
Predict outcomes under specified hypothetical treatment strategies.
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Causal Effect Estimation
Estimate the causal effect of an exposure, treatment, intervention, or policy on an outcome.